PDGFR) and transfect mammalian cells to express the fusion protein on the cell surface
References 1 AnnunziataG.MaistoM.SchisanoC.CiampagliaR.NarcisoV.HassanS
Finally, ceramide can follow four major catabolic pathways: (1) phosphorylated by the ceramide kinase (CERK) to form ceramide-1-phosphate (C1P), (2) incorporated into sphingomyelin-by-sphingomyelin synthase (SMS) activity, (3) or into glucosylceramide by the activation of glucosylceramide synthases (GCS), leading to the generation of complex SLs like cerebrosides, gangliosides, sulfatides and globosides
Human CHAC1 protein degrades glutathione, and mrna induction is regulated by the transcription factors ATF4 and ATF3 and a bipartite ATF/CRE regulatory element
Badve SV, Bilal A, Lee MMY, Sattar N, Gerstein HC, Ruff CT, et al